Familial Hypothalamic Diabetes Insipidus in Rats

@article{Valtin1962FamilialHD,
  title={Familial Hypothalamic Diabetes Insipidus in Rats},
  author={Heinz Valtin and Henry A. Schroeder and Kurt Benirschke and H W Sokol},
  journal={Nature},
  year={1962},
  volume={196},
  pages={1109-1110}
}
WE are at present raising a strain of rats with hypothalamic, vasopressin-sensitive diabetes insipidus. This disease arose as an apparently spontaneous mutation along with a mutation for albinism in some of the affected animals, from a pure strain of Long-Evans hooded rats being bred for an unrelated research problem not involving radioactivity. The original litter of 17 included 4 albino females with diabetes insipidus, one albino male without diabetes insipidus, and one hooded male and one… CONTINUE READING

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