Familial Churg-Strauss syndrome in two sisters.

  title={Familial Churg-Strauss syndrome in two sisters.},
  author={Naomi Tsurikisawa and Sonoko Morita and Takahiro Tsuburai and Chiyako Oshikata and Emiko Ono and Masami Taniguchi and Hiroshi Saito and Yukiyoshi Yanagihara and Kazuo Akiyama},
  volume={131 2},
Churg-Strauss syndrome (CSS) is an uncommon systemic vasculitis with an increase in the number of eosinophils in the peripheral blood and tissues. Its pathogenesis is unknown, and there is no evidence that genetic factors influence susceptibility to this disease. We present a case of familial CSS in two sisters with atopic-type bronchial asthma and negative perinuclear anti-neutrophil cytoplasmic antibody results. We investigated the human leukocyte antigen typing of the sisters and their six… CONTINUE READING