Familial, Anthropometric, and Metabolic Associations of Intramyocellular Lipid Levels in Prepubertal Males

@article{Ashley2002FamilialAA,
  title={Familial, Anthropometric, and Metabolic Associations of Intramyocellular Lipid Levels in Prepubertal Males},
  author={Mellisa A Ashley and Alexandra J Buckley and Alison L Criss and Julie A Ward and Allan Kemp and Sarah Garnett and Christopher T Cowell and Louise A. Baur and Campbell H Thompson},
  journal={Pediatric Research},
  year={2002},
  volume={51},
  pages={81-86}
}
The cause of skeletal muscle insulin resistance is unclear, but high levels of intramyocellular lipids are often present in affected individuals. We aimed to establish the metabolic, familial, and anthropometric associations of intramyocellular lipid in a pediatric population. We studied 41 boys aged 6.9–9.9 y and 23 of their mothers by proton magnetic resonance spectroscopy. We related muscle lipid levels to important factors that define an increased risk of developing insulin resistance in… CONTINUE READING

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