Famciclovir for the Treatment of Acute Herpes Zoster: Effects on Acute Disease and Postherpetic Neuralgia: A Randomized, Double-Blind, Placebo-Controlled Trial

@article{Tyring1995FamciclovirFT,
  title={Famciclovir for the Treatment of Acute Herpes Zoster: Effects on Acute Disease and Postherpetic Neuralgia: A Randomized, Double-Blind, Placebo-Controlled Trial},
  author={Stephen K. Tyring and Rick Barbarash and James Nahlik and Anthony Cunningham and John Marley and Madalene Heng and Terry M. Jones and T L Rea and Ron J Boon and Robin L. Saltzman},
  journal={Annals of Internal Medicine},
  year={1995},
  volume={123},
  pages={89-96}
}
Herpes zoster (shingles) develops in as many as 20% of all persons [1]. The characteristic zoster rash is often accompanied by substantial pain, dysesthesias, and skin hypersensitivity. The unmet challenge in the management of patients with acute zoster is the alleviation of chronic pain. In many patients, pain resolves once the affected area of skin returns to normal. However, some patients continue to experience pain long after the lesions have healed; this pain is commonly called… 

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...

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