False-positive somatostatin receptor scintigraphy due to an accessory spleen.


A patient with previous left caudal pancreatectomy and splenectomy presented with Zollinger-Ellison syndrome. Abdominal CT and endoscopic ultrasonography revealed a mass in the splenic area. Somatostatin receptor scintigraphy showed a nodular increase of the uptake corresponding to the lesion detected with conventional imaging. A second laparotomy was performed and the mass was resected. Histological analysis showed that the nodular lesion was an accessory spleen. Since physiologic uptake of 111In-pentetreotide is seen in the spleen, an accessory spleen mimicking a tumor, specially after previous splenectomy, may result in false-positive somatostatin receptor scintigraphy.


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@article{Lebtahi1997FalsepositiveSR, title={False-positive somatostatin receptor scintigraphy due to an accessory spleen.}, author={Rachida Lebtahi and Guillaume Cadiot and J P Marmuse and Ch Vissuzaine and Yolande Petegnief and Anne Courillon-Mallet and Daniel Cattan and Michel Mignon and Dominique Le Guludec}, journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine}, year={1997}, volume={38 12}, pages={1979-81} }