False-positive COVID-19 results: hidden problems and costs

  title={False-positive COVID-19 results: hidden problems and costs},
  author={Elena Surkova and Vladyslav Nikolayevskyy and Francis Drobniewski},
  journal={The Lancet. Respiratory Medicine},
  pages={1167 - 1168}

The Impact of False Positive COVID-19 Result

Doctors should consider the possibility of false-positive results and utilize other investigation tools to further diagnose suspicious cases, as seen in a 54-years-old female who was misdiagnosed as COVID-19.

Estimate false‐negative RT‐PCR rates for SARS‐CoV‐2. A systematic review and meta‐analysis

This work aimed to estimate, through a systematic review of the literature, the rate of RT‐PCR false negatives at initial testing for COVID‐19, which is used to identify symptomatic or asymptomatic patients infected by SARS‐CoV‐2.

Suspected Tuberculous Pleurisy and Coronavirus Disease 2019 Comorbidity

Data concerning COVID-19 diagnostics are insufficient at present and it is important to make comprehensive judgments regarding the diagnosis and treatment of patients as well as public health.

Prospective Clinical Assessments of Hospitalized Patients With Positive SARS-CoV-2 PCR Tests for Necessity of Isolation

One hundred forty-eight patients with positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients were deemed noninfectious, most with evidence of prior infection, and managed on standard precautions without evidence of transmission.

Immunity and infectivity in covid-19

Decisions related to transmission risk must take into account all relevant factors, including the overall risk of infection in the community, the individual’s ability to comply with prevention measures, their home and work environment, and the risk profile of their likely future close contacts.

Influenza A or COVID-19 Reinfection? Making the Right Diagnosis during the COVID-19 Pandemic

A 51-year-old African American single mother with a past medical history of Hypertension, HIV, Obesity, Prediabetes, Hyperlipidemia, and Vitamin D deficiency is diagnosed with SARS-CoV-2.

COVID-19 and Dentistry

Dentistry is a healthcare profession requiring close contacts between the dental practitioner and the patient. In particular, many dental procedures generate aerosols and droplets which are proved to

SARS-CoV-2 During Abdominal Operations: Are Surgeons at Risk?

This is a prospective cross-sectional study including adult patients with confirmed COVID-19 who underwent surgery at a single institution and found SARS-CoV-2 was not found in the peritoneal cavity of 6 patients undergoing abdominal surgery.

COVID-19: Balancing between Transmission Suppression and Immunity

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Disparity in clinical characteristics between 2019 novel coronavirus pneumonia and leptospirosis

The clinical disparities may facilitate the therapeutic management of these two diseases, and it is important to suspect leptospirosis in cases with a similar presentation of COVID-19.



Interpreting a covid-19 test result

The availability of the complete genome of covid-19 early in the epidemic facilitated development of tests to detect viral RNA, which enables infected individuals to be identified and isolated to reduce spread and provides knowledge of regional and national rates of infection to inform public health interventions.

Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards

Correlation between successful isolation of virus in cell culture and Ct value of quantitative RT-PCR targeting E gene suggests that patients with Ct above 33–34 using the RT- PCR system are not contagious and thus can be discharged from hospital care or strict confinement for non-hospitalized patients.

False-negative results of initial RT-PCR assays for COVID-19: A systematic review

The findings reinforce the need for repeated testing in patients with suspicion of SARS-Cov-2 infection given that up to 29% of patients could have an initial RT-PCR false-negative result.

False positives in reverse transcription PCR testing for SARS-CoV-2

The high false discovery rate that results, when prevalence is low, from false positive rates typical of RT-PCR assays of RNA viruses raises questions about the usefulness of mass testing; and indicates that across a broad range of likely prevalences, positive test results are more likely to be wrong than are negative results, contrary to public health advice about SARS-CoV-2 testing.

European Centre for Disease Prevention and Control.

  • R. Evans
  • Medicine, Business
    Nursing standard (Royal College of Nursing (Great Britain) : 1987)
  • 2014
The European Centre for Disease Prevention and Control was set up in 2005 to strengthen Europe's defences against infectious diseases. The centre is an independent agency of the European Union and is

Weekly coronavirus disease 2019 (COVID19) surveillance report. Summary of COVID19 surveillance systems

    Impact of false ­ positives and false ­ negatives in the UK ’ s COVID ­ 19 RT ­ PCR testing programme

      Interpreting a covid19 test result

      • BMJ
      • 2020

      Weekly coronavirus disease 2019 (COVID-19) surveillance report. Summary of COVID-19 surveillance systems

        Contamination at CDC lab delayed rollout of coronavirus tests