Failure to remove true sentinel nodes can cause failure of the sentinel node biopsy technique: Evidence from antimony concentrations in false-negative sentinel nodes from melanoma patients

@article{Mbbs2004FailureTR,
  title={Failure to remove true sentinel nodes can cause failure of the sentinel node biopsy technique: Evidence from antimony concentrations in false-negative sentinel nodes from melanoma patients},
  author={Richard A. Scolyer Mbbs and John F Thompson and L Li and Alison Beavis BSc and Michael Dawson and Phillip Doble and Vivian S. K. Ka and J G Mckinnon and Robyne Soper BSc and R. F. Uren and Helen M. Shaw and Jonathan R. Stretch DPhil and Stanley W. McCarthy Mbbs},
  journal={Annals of Surgical Oncology},
  year={2004},
  volume={11},
  pages={174S-178S}
}
We have recently found that antimony (originating from the technetium 99m antimony trisulfide colloid, used for preoperative lymphoscintigraphy) can be measured in tissue sections from archival paraffin blocks of sentinel nodes (SNs) by means of inductively coupled plasma mass spectrometry (ICP-MS) to confirm that removed nodes are ture SNs. We performed a retrospective analysis of antimony concentrations in all our false-negative (FN) SNs to determine whether errors in lymphadenectomy (i.e… CONTINUE READING
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