Failure to reconstitute CD4+ T-cells despite suppression of HIV replication under HAART.

@article{Aiuti2006FailureTR,
  title={Failure to reconstitute CD4+ T-cells despite suppression of HIV replication under HAART.},
  author={Fernando Aiuti and Ivano Mezzaroma},
  journal={AIDS reviews},
  year={2006},
  volume={8 2},
  pages={88-97}
}
HAART in HIV-1-infected individuals has a broad spectrum of clinical outcomes. In the majority of patients, plasma viral load becomes undetectable and CD4+ T-cells increase over time. However, in a number of subjects a discrepancy between plasma viral load and the CD4+ T-cell recovery is observed. CD4+ T-cell count can rise despite persistently detectable plasma viral load (virologic nonresponders), or conversely does not increase despite full plasma viral load suppression (immunologic… CONTINUE READING