Failure to make normal alpha ryanodine receptor is an early event associated with the crooked neck dwarf (cn) mutation in chicken.

Abstract

We have investigated the molecular basis of the Crooked Neck Dwarf (cn) mutation in embryonic chickens. Using biochemical and pharmacological techniques we are unable to detect normal alpha ryanodine receptor (RyR) protein in intact cn/cn skeletal muscle. Extremely low levels of alpha RyR immunoreactivity can be observed in mutant muscles, but the… (More)

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Cite this paper

@article{Airey1993FailureTM, title={Failure to make normal alpha ryanodine receptor is an early event associated with the crooked neck dwarf (cn) mutation in chicken.}, author={Judith A. Airey and M D Baring and Christoph Beck and Yogarany Chelliah and Thomas J. Deerinck and Mark H. Ellisman and Lucien J. Houenou and D D Mckemy and John L. Sutko and Jane A. Talvenheimo}, journal={Developmental dynamics : an official publication of the American Association of Anatomists}, year={1993}, volume={197 3}, pages={169-88} }