Failure to detect the presence of Chlamydia pneumoniae in sarcoid pathology specimens.

@article{Blasi1997FailureTD,
  title={Failure to detect the presence of Chlamydia pneumoniae in sarcoid pathology specimens.},
  author={Francesco Blasi and Gianfranco Rizzato and Marcello Gambacorta and Roberto Cosentini and Rita Raccanelli and Paolo Tarsia and Cristina Arosio and Elisa Savini and Carlo Cantoni and L. Fagetti and Luigi Allegra},
  journal={The European respiratory journal},
  year={1997},
  volume={10 11},
  pages={2609-11}
}
The pathogenesis of sarcoidosis is not yet known. On the basis of seroepidemiological data, an association between Chlamydia pneumoniae infection and sarcoidosis has been suggested, but so far no study has addressed the direct detection of this agent in the affected tissues. The aim of the present study was to detect C. pneumoniae deoxyribonucleic acid (DNA) within sarcoid tissue specimens by means of a two-step polymerase chain reaction. Lung biopsy specimens of 33 patients with histologically… CONTINUE READING