Failure of vaccination to prevent outbreaks of foot-and-mouth disease.

@article{Woolhouse1996FailureOV,
  title={Failure of vaccination to prevent outbreaks of foot-and-mouth disease.},
  author={Mark E. J. Woolhouse and Daniel T. Haydon and April Pearson and Richard Paul Kitching},
  journal={Epidemiology and infection},
  year={1996},
  volume={116 3},
  pages={
          363-71
        }
}
Outbreaks of foot-and-mouth disease persist in dairy cattle herds in Saudi Arabia despite revaccination at intervals of 4-6 months. Vaccine trials provide data on antibody responses following vaccination. Using this information we developed a mathematical model of the decay of protective antibodies with which we estimated the fraction of susceptible animals at a given time after vaccination. The model describes the data well, suggesting over 95% take with an antibody half-life of 43 days. Farm… CONTINUE READING

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Predicting and comparing long-term measles antibody profiles of different immunization policies.

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