Failure of trabecular bone with simulated lytic defects can be predicted non-invasively by structural analysis.

@article{Hong2004FailureOT,
  title={Failure of trabecular bone with simulated lytic defects can be predicted non-invasively by structural analysis.},
  author={James Goh Cho Hong and Greg D Cabe and John R Tedrow and John A. Hipp and Brian S. Snyder},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={2004},
  volume={22 3},
  pages={479-86}
}
Pathologic fracture is a significant risk for patients afflicted with metastatic or benign skeletal tumors. The quandary for physicians who treat these patients is that after making the diagnosis they must try to predict the load bearing capacity of the involved bone and the fracture risk from images seen in radiological examinations. Since bone fails at a relatively constant strain independent of density we demonstrate that using a mechanics of materials approach that the cross-sectional… CONTINUE READING