Failure of pimozide and metergoline to antagonize the RDS-127-induced facilitation of ejaculatory behavior

@article{Clark1986FailureOP,
  title={Failure of pimozide and metergoline to antagonize the RDS-127-induced facilitation of ejaculatory behavior},
  author={J. T. Clark and E. Smith},
  journal={Physiology & Behavior},
  year={1986},
  volume={37},
  pages={47-52}
}
  • J. T. Clark, E. Smith
  • Published 1986
  • Psychology, Medicine
  • Physiology & Behavior
  • Metergoline, a serotonin-receptor antagonist, when administered in either an ascorbic acid or ethanol containing vehicle was without effect on male rat copulatory behavior (3 mg/kg, 90 minutes pretest). When initially dissolved in several drops of acetic acid, however, the same dose of metergoline dramatically suppressed male rat sexual behavior. Thus, one-half of the treated rats failed to intromit and ejaculate, and those displaying the behaviors exhibited elongated intercopulatory and… CONTINUE READING
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