Failure of physiologic transformation of the spiral arteries in the placental bed in preterm premature rupture of membranes.

@article{Kim2002FailureOP,
  title={Failure of physiologic transformation of the spiral arteries in the placental bed in preterm premature rupture of membranes.},
  author={Yeon Kim and Tinnakorn Chaiworapongsa and Ricardo Pay{\'a}n Gom{\'e}z and Emmanuel Bujold and Bo Hyun Yoon and Siegfried Rotmensch and Howard T. Thaler and Roberto Romero},
  journal={American journal of obstetrics and gynecology},
  year={2002},
  volume={187 5},
  pages={1137-42}
}
OBJECTIVE The purpose of this study was to determine whether failure of physiologic transformation of the spiral arteries occurs in patients with preterm premature rupture of membranes (PROM). STUDY DESIGN A cross-sectional study was designed to examine the histopathologic findings in the placental bed and placenta of patients with preterm PROM, preeclampsia, and normal women at term. Immunohistochemistry with cytokeratin 7 and periodic acid-Schiff (PAS) were used to detect trophoblast and… CONTINUE READING