Failure of intravenously infused spleen cells bearing a minor histoincompatibility to delay rejection of skin grafts bearing additional antigens.


Intravenous infusions of spleen cells bearing single minor H antigens have been shown to induce an antigen-specific prolongation of survival of subsequently applied skin grafts bearing the infused antigen. In this report it is shown that i.v. infusion of spleen cells bearing only H-Y as an alloantigen fails to prolong the survival of subsequently applied… (More)


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