Failure of initial VEGF-targeted therapy in metastatic renal cell carcinoma (mRCC): What next?

5098 Background: The characterization and efficacy of second-line targeted therapy in patients with metastatic RCC who failed first-line VEGF-targeted therapy in a population-based setting is of clinical relevance but remains to be assessed. METHODS Provincial registries and clinical databases from seven cancer centers (3 in US and 4 in Canada) identified… CONTINUE READING