Failure of cidofovir in HIV-associated multicentric Castleman disease.

  title={Failure of cidofovir in HIV-associated multicentric Castleman disease.},
  author={Alice B{\'e}r{\'e}zn{\'e} and F{\'e}lix Agbalika and Eric Oksenhendler},
  volume={103 11},
  pages={4368-9; author reply 4369}
Multicentric Castleman disease (MCD) is a distinct lymphoproliferative disorder characterized by lymphadenopathy with angiofollicular hyperplasia and plasma cell infiltration. Patients typically have fever associated with lymphadenopathy, hepatosplenomegaly, respiratory symptoms, peripheral edema, cytopenia, hypergammaglobulinemia, hypoalbuminemia, and high levels of serum C reactive protein (CRP).1 In the context of HIV infection, MCD is associated with Kaposi sarcoma–associated herpesvirus… CONTINUE READING


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