Failure of aged rats to accumulate eosinophils in allergic inflammation of the airway.

Abstract

To investigate the effect of aging on the allergic airway response, we examined the bronchoconstrictive responses and cellular inflammatory changes in a rat model of bronchial asthma by evaluating young and old animals. Two different age groups of Brown-Norway rats, actively sensitized by injection of ovalbumin into the foot pads, were used: 7 to 8 weeks… (More)

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@article{Yagi1997FailureOA, title={Failure of aged rats to accumulate eosinophils in allergic inflammation of the airway.}, author={Takao Yagi and A. Sato and H. Hayakawa and Koichi Ide}, journal={The Journal of allergy and clinical immunology}, year={1997}, volume={99 1 Pt 1}, pages={38-47} }