Failure of Noninvasive Ventilation for De Novo Acute Hypoxemic Respiratory Failure: Role of Tidal Volume*

@article{Carteaux2016FailureON,
  title={Failure of Noninvasive Ventilation for De Novo Acute Hypoxemic Respiratory Failure: Role of Tidal Volume*},
  author={Guillaume Carteaux and Teresa Mill{\'a}n-Guilarte and Nicolas de Prost and Keyvan Razazi and Shariq Abid and Arnaud W. Thille and Fr{\'e}d{\'e}rique Schortgen and Laurent J. Brochard and Christian Brun-Buisson and Armand Mekontso Dessap},
  journal={Critical Care Medicine},
  year={2016},
  volume={44},
  pages={282–290}
}
OBJECTIVES A low or moderate expired tidal volume can be difficult to achieve during noninvasive ventilation for de novo acute hypoxemic respiratory failure (i.e., not due to exacerbation of chronic lung disease or cardiac failure. [] Key MethodDESIGN Prospective observational study. SETTING Twenty-four bed university medical ICU. PATIENTS Consecutive patients receiving noninvasive ventilation for acute hypoxemic respiratory failure between August 2010 and February 2013.
Initial Noninvasive Oxygenation Strategies in Subjects With De Novo Acute Hypoxemic Respiratory Failure
TLDR
Among subjects with hypoxemic respiratory failure, NIV was associated with a significant reduction in intubation rates but not short- or long-term mortality when compared to conventional oxygen therapy, and there was no significant difference between NIV and HFNC or between HFNC and conventional oxygen regarding all outcomes.
Early Inspiratory Effort Assessment by Esophageal Manometry Predicts Noninvasive Ventilation Outcome in De Novo Respiratory Failure. A Pilot Study
TLDR
The magnitude of inspiratory effort relief as assessed by ΔPes variation within the first 2 hours of NIV was an early and accurate predictor of N IV outcome at 24 hours.
Noninvasive ventilation versus oxygen therapy in patients with acute respiratory failure.
TLDR
In postoperative cardiothoracic patients, HFOT could be an alternative to NIV in the management of acute respiratory failure, and growing use of HFOT will lead to new studies comparing NIV versus HFOT in view of more precisely defining the appropriate indications for each treatment.
Noninvasive Ventilation in Acute Hypoxemic Nonhypercapnic Respiratory Failure: A Systematic Review and Meta-Analysis
TLDR
There is no sufficient scientific evidence to recommend bilevel positive airway pressure or helmet due to the limited number of trials available, and large rigorous randomized trials are needed to answer these questions definitely.
Noninvasive ventilation as acute therapy
TLDR
Noninvasive ventilation should be cautiously used in patients with de-novo respiratory failure, the vast majority of whom meet the criteria for acute respiratory distress syndrome, and new studies are needed to compare NIV versus high-flow oxygen therapy so as to better define the appropriate indications for each treatment.
Predictors of Intubation in Patients With Acute Hypoxemic Respiratory Failure Treated With a Noninvasive Oxygenation Strategy*
TLDR
In patients with acute hypoxemic respiratory failure breathing spontaneously, the respiratory rate was a predictor of intubation under standard oxygen, but not under high-flow nasal cannula oxygen or noninvasive ventilation.
Noninvasive Ventilatory Support in Acute Respiratory Distress Syndrome
TLDR
An important emerging concern comes from the fact that some non-intubated patients with a high respiratory drive may develop an injurious breathing pattern and self-inflict lung injury and the optimal treatment may then be sedation, intubation, and application of a lung-protective ventilation.
Noninvasive oxygenation strategies in adult patients with acute respiratory failure: a protocol for a systematic review and network meta-analysis
TLDR
This network meta-analysis is to summarize the evidence and compare the effect of noninvasive oxygenation strategies on mortality and need for invasive mechanical ventilation in patients with acute hypoxemic respiratory failure and improve the understanding of the limitations of the available literature.
Noninvasive Ventilation for Acute Hypoxemic Respiratory Failure/ARDS - is There a Role?
TLDR
Noninvasive ventilation has assumed an important role in the management of acute respiratory failure over the past 15 to 20 years, but the application of NIV in patients with so called de novo acute hypoxemic respiratory failure related to pneumonia or acute respiratory distress syndrome has long been known to be more challenging.
Acute Respiratory Failure: Non-invasive Ventilation and High Flow Nasal Cannula
TLDR
Low evidence supports the use of NIV as a weaning strategy from invasive mechanical ventilation, and high flow nasal cannula has emerged as an increasingly common support modality for acute hypoxic respiratory and may be used as a substitute or adjunct to NIV.
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