Failure at the primary site following multimodality treatment in advanced head and neck cancer.

@article{Vikram1984FailureAT,
  title={Failure at the primary site following multimodality treatment in advanced head and neck cancer.},
  author={B. Sreenivasa Vikram and Elliot W Strong and Jatin P Shah and Ronald H. Spiro},
  journal={Head & neck surgery},
  year={1984},
  volume={6 3},
  pages={720-3}
}
Recurrence at the primary site is an important cause of morbidity and mortality in head and neck cancer. In patients with stages III and IV disease treated surgically at Memorial Sloan-Kettering Cancer Center between 1960 and 1970, cancer recurred at the primary site in 39% even when the margins had been deemed satisfactory, and in 73% when the margins were unsatisfactory. Between 1975 and 1980, we treated 114 previously untreated patients with stages III and IV epidermoid carcinoma of the oral… CONTINUE READING

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