Faecal steroids and colorectal carcinogenesis.

  title={Faecal steroids and colorectal carcinogenesis.},
  author={Robert Wyn Owen},
  journal={Scandinavian journal of gastroenterology},
  volume={32 Suppl 222},
BACKGROUND Colorectal cancer is a major disease of Western civilizations and diet may account for approximately 35% of cases. Epidemiologic studies reveal that the major dietary constituents implicated in the disease process are fat/red meat (causative) and fibre (protective). From this standpoint, toxicologists have evaluated a plethora of dietary and intestinal biochemical characteristics and steroids; the bile acids especially have received a great deal of attention. Formerly, bile acids and… CONTINUE READING