Factors that influence induction of gastroesophageal reflux in normal human subjects

@article{Dent2005FactorsTI,
  title={Factors that influence induction of gastroesophageal reflux in normal human subjects},
  author={J. Dent and W. Dodds and W. Hogan and J. Toouli},
  journal={Digestive Diseases and Sciences},
  year={2005},
  volume={33},
  pages={270-275}
}
  • J. Dent, W. Dodds, +1 author J. Toouli
  • Published 2005
  • Medicine
  • Digestive Diseases and Sciences
  • Findings from recent studies indicate that transient relaxation of the lower esophageal sphincter (LES) is an important contributory mechanism to spontaneous episodes of gastroesophageal reflux (GER) in normal subjects as well as in patients with reflux esophagitis. Our study aim was to evaluate the interrelationship between reduction of LES pressure and elevation of intraabdominal pressure in the induction of GER in healthy subjects. Seven volunteers were studied supine after gastric loading… CONTINUE READING
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