Factors predictive of response to hormone therapy in breast cancer.

  title={Factors predictive of response to hormone therapy in breast cancer.},
  author={Francesca Rastelli and Sergio Crispino},
  volume={94 3},
AIMS AND BACKGROUND Approximately half of metastatic breast cancers expressing estrogen and/or progesterone receptors responds to endocrine therapy, and postoperative adjuvant endocrine therapy provides about a 50% reduction in the development of recurrent disease. A number of publications have focused on the correlation of biomarkers, in particular estrogen and progesterone receptors and HER-2/neu status as well as different gene profiles, multigene assays and genetic polymorphisms with… CONTINUE READING


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