Factors of concern in a human 3D cellular airway model exposed to aerosols of nanoparticles.

@article{Kooter2017FactorsOC,
  title={Factors of concern in a human 3D cellular airway model exposed to aerosols of nanoparticles.},
  author={Ingeborg M. Kooter and Mariska Gr{\"o}llers-Mulderij and Evert Duistermaat and Frieke C. Kuper and Eric D. Schoen},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2017},
  volume={44},
  pages={
          339-348
        }
}
Mucilair 3D bronchial airway models, cultured at an air-liquid interface, were exposed to aerosols of copper oxide (CuO) nanoparticles in Vitrocell air exposure modules. Four cell donors, four exposure modules and four exposure concentrations were varied within four different exposure sessions using a statistical experimental design called a hyper-Graeco-Latin square. Analysis of variance techniques were used to investigate the effects of these factors on release and RNA expression of… CONTINUE READING
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