Factors modulating benzidine carcinogenicity bioassay.

  title={Factors modulating benzidine carcinogenicity bioassay.},
  author={Stan D Vesselinovitch and K Narasimha Rao and N. Mihailovich},
  journal={Cancer research},
  volume={35 10},
An integrated series of studies was presented in which several factors were assessed as to their capability to influence the outcome of carcinogenicity of benzidine dihydrochloride in mice. In all studies C57BL/6J X C3HeB/FeJ F1 mice of both sexes were utilized. Animals were either 6 or 1 week of age at the beginning of carcinogenic treatment. Six-week-old mice were exposed to p.o. administration of carcinogen delivered either in food (50 or 100 ppm daily) or by stomach intubation at equivalent… CONTINUE READING
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