Factors influencing the assay of Inoue-Melnick virus.

@article{Nishibe1987FactorsIT,
  title={Factors influencing the assay of Inoue-Melnick virus.},
  author={Yoko Nishibe and Yasuhiro Inoue and Joseph L. Melnick},
  journal={Journal of virological methods},
  year={1987},
  volume={17 3-4},
  pages={293-8}
}
We describe factors influencing the assay of Inoue-Melnick virus (IMV) and practical comments for its assay. MRC-5 cells at a population doubling level (PDL) of more than 32 were more sensitive than younger cells for demonstrating cytopathic effect (CPE) of the virus. The PDL of MRC-5 cells also influenced the virus yield, particularly when the amount of… CONTINUE READING