Factors in the pathophysiology of the liver ischemia-reperfusion injury.

@article{MontalvoJav2008FactorsIT,
  title={Factors in the pathophysiology of the liver ischemia-reperfusion injury.},
  author={Eduardo Esteban Montalvo-Jav{\'e} and Tom{\'a}s Escalante-Tattersfield and Jos{\'e} Arturo Ortega-Salgado and Enrique Pi{\~n}a and David A. Geller},
  journal={The Journal of surgical research},
  year={2008},
  volume={147 1},
  pages={153-9}
}
Hepatic ischemia-reperfusion injury is commonplace in liver surgery, particularly in hepatic transplantation, hepatic resection, and trauma. The signaling events contributing to local hepatocellular damage are diverse and complex and involve the interaction between hepatocytes, sinusoidal endothelial cells, Kupffer cells, as well as infiltrating neutrophils, macrophages, and platelets. Signaling mediators include cytokines, reactive oxygen and nitrogen species, calcium, complement, and several… CONTINUE READING

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