Factors in snake venoms that increase capillary permeability.

@article{Miller1989FactorsIS,
  title={Factors in snake venoms that increase capillary permeability.},
  author={Richard A. Miller and Anthony T. Tu},
  journal={The Journal of pharmacy and pharmacology},
  year={1989},
  volume={41 11},
  pages={792-4}
}
Capillary permeability increasing (CPI) activity is a phenomenon of the microvasculature caused by many agents such as snake venoms, histamine, 5-hydroxytryptamine (5-HT), prostaglandins and leukotrienes. Since no systematic study has been done to determine what components of snake venom cause CPI activity, a CPI factor from Naja naja atra (Taiwan cobra) venom was isolated using intravenous injections of Evan's blue dye as the indicator of increased permeability and the factor's properties were… CONTINUE READING

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The histamine H1-receptor blockers diphenhydramine , promethazine , and cyproheptadine were effective against both venoms in preventing increased capillary permeability .
The histamine H1-receptor blockers diphenhydramine , promethazine , and cyproheptadine were effective against both venoms in preventing increased capillary permeability .
The histamine H1-receptor blockers diphenhydramine , promethazine , and cyproheptadine were effective against both venoms in preventing increased capillary permeability .
The histamine H1-receptor blockers diphenhydramine , promethazine , and cyproheptadine were effective against both venoms in preventing increased capillary permeability .
The histamine H1-receptor blockers diphenhydramine , promethazine , and cyproheptadine were effective against both venoms in preventing increased capillary permeability .
The histamine H1-receptor blockers diphenhydramine , promethazine , and cyproheptadine were effective against both venoms in preventing increased capillary permeability .
Since no systematic study has been done to determine what components of snake venom cause CPI activity , a CPI factor from Naja naja atra ( Taiwan cobra ) venom was isolated using intravenous injections of Evan 's blue dye as the indicator of increased permeability and the factor 's properties were extensively studied .
permeability increasing ( CPI ) activity is a phenomenon of the microvasculature caused by many agents such as snake venoms , histamine , 5-hydroxytryptamine ( 5-HT ) , prostaglandins and leukotrienes .
permeability increasing ( CPI ) activity is a phenomenon of the microvasculature caused by many agents such as snake venoms , histamine , 5-hydroxytryptamine ( 5-HT ) , prostaglandins and leukotrienes .
However , CPI activity is not due to cardiotoxins alone as the presynaptic neurotoxin , Mojave toxin , also showed CPI activity .
However , CPI activity is not due to cardiotoxins alone as the presynaptic neurotoxin , Mojave toxin , also showed CPI activity .
Since no systematic study has been done to determine what components of snake venom cause CPI activity , a CPI factor from Naja naja atra ( Taiwan cobra ) venom was isolated using intravenous injections of Evan 's blue dye as the indicator of increased permeability and the factor 's properties were extensively studied .
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