Factors contributing to muscle wasting and dysfunction in COPD patients

@article{Wst2007FactorsCT,
  title={Factors contributing to muscle wasting and dysfunction in COPD patients},
  author={Rob C I W{\"u}st and Hans Degens},
  journal={International Journal of Chronic Obstructive Pulmonary Disease},
  year={2007},
  volume={2},
  pages={289 - 300}
}
Many patients with chronic obstructive pulmonary disease (COPD) suffer from exercise intolerance. In about 40% of the patients exercise capacity is limited by alterations in skeletal muscle rather than pulmonary problems. Indeed, COPD is often associated with muscle wasting and a slow-to-fast shift in fiber type composition resulting in weakness and an earlier onset of muscle fatigue, respectively. Clearly, limiting muscle wasting during COPD benefits the patient by improving the quality of… CONTINUE READING