Factors concerning the immunity to poxvirus infection.

@article{Tagaya1977FactorsCT,
  title={Factors concerning the immunity to poxvirus infection.},
  author={Isamu Tagaya and Minetaro Arita and Hideaki Amano and Yoshiaki Ueda},
  journal={Annales de microbiologie},
  year={1977},
  volume={128 3},
  pages={409-16}
}
Two kinds of early antigens were shown in vaccinia-infected cells, one heat (56 degrees, 30 min)-stable (ES antigen) and the other heat-labile (EL antigen). Both antigens do not induce circulating neutralizing antibody in rabbits, but resistance to intradermal inoculation of active virus was observed when animals were immunized with either antigen in… CONTINUE READING