Factors characterizing Staphylococcus epidermidis invasiveness determined by comparative genomics.

@article{Yao2005FactorsCS,
  title={Factors characterizing Staphylococcus epidermidis invasiveness determined by comparative genomics.},
  author={Yufeng Yao and Daniel E. Sturdevant and Amer E. Villaruz and Lin Xu and Qian Gao and Michael Otto},
  journal={Infection and immunity},
  year={2005},
  volume={73 3},
  pages={1856-60}
}
Virulence mechanisms of the leading nosocomial pathogen Staphylococcus epidermidis are poorly understood. We used microarray-based genome-wide comparison of clinical and commensal S. epidermidis strains to identify putative virulence determinants. Our study revealed high genetic variability of the S. epidermidis genome, new markers for invasiveness of S. epidermidis, and potential targets for drug development against S. epidermidis infections. 
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