Factors associated with the development of peanut allergy in childhood.

@article{Lack2003FactorsAW,
  title={Factors associated with the development of peanut allergy in childhood.},
  author={Gideon Lack and Deborah Fox and Kate Northstone and Jean Golding},
  journal={The New England journal of medicine},
  year={2003},
  volume={348 11},
  pages={
          977-85
        }
}
BACKGROUND The prevalence of peanut allergy appears to have increased in recent decades. Other than a family history of peanut allergy and the presence of atopy, there are no known risk factors. METHODS We used data from the Avon Longitudinal Study of Parents and Children, a geographically defined cohort study of 13,971 preschool children, to identify those with a convincing history of peanut allergy and the subgroup that reacted to a double-blind peanut challenge. We first prospectively… Expand
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This prevalence study is the first in North America to corroborate history with confirmatory testing and the largest worldwide to incorporate these techniques and has shown that, even with conservative assumptions, prevalence exceeds 1.0%. Expand
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Antenatal risk factors for peanut allergy in children
  • K. Binkley, C. Leaver, J. Ray
  • Medicine
  • Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
  • 2011
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The risk of childhood peanut allergy was not modified by the following common maternal exposures in pregnancy: Rh immune globulin, folic acid or peanut-containing foods. Expand
Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants.
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In this cohort of infants with likely milk or egg allergy, maternal ingestion of peanut during pregnancy was strongly associated with a high level of peanut sensitization. Expand
Household almond and peanut consumption is related to the development of sensitization in young children.
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Assessment of the association between consumption of various types of nuts (almonds, walnuts, and peanuts) in domestic settings by family members who live with the children and sensitization to these foods in children younger than 18 months found that home consumption of almonds, AD, and egg sensitization had a statistically significant association with sensitized to this nut. Expand
Is the prevalence of peanut allergy increasing? A 5-year follow-up study in children in Montreal.
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This is the first North American study to document temporal trends in peanut allergy prevalence by corroborating history with confirmatory tests, and the results suggest a stable prevalence, but wide CIs preclude definitive conclusions. Expand
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