Factors associated with the development of peanut allergy in childhood.

  title={Factors associated with the development of peanut allergy in childhood.},
  author={Gideon Lack and Deborah Fox and Kate Northstone and Jean Golding},
  journal={The New England journal of medicine},
  volume={348 11},
BACKGROUND The prevalence of peanut allergy appears to have increased in recent decades. Other than a family history of peanut allergy and the presence of atopy, there are no known risk factors. METHODS We used data from the Avon Longitudinal Study of Parents and Children, a geographically defined cohort study of 13,971 preschool children, to identify those with a convincing history of peanut allergy and the subgroup that reacted to a double-blind peanut challenge. We first prospectively… 
Peanut allergy: is maternal transmission of antigens during pregnancy and breastfeeding a risk factor?
Early exposure to peanut allergens, whether in utero or through human breast milk, seems to increase the risk of developing peanut allergy.
Peanut allergy in Mexican children: what is the effect of age at first consumption?
The results of the present study showed that the late introduction of peanuts to children increases the risk of developing a peanut allergy.
Peanut sensitization in a group of allergic Egyptian children
Peanut allergy does not seem to be rare in atopic children in Egypt and skin prick and specific IgE testing are effective screening tools to determine candidates for peanut oral challenging.
Household peanut consumption as a risk factor for the development of peanut allergy.
Prevalence of peanut allergy in primary-school children in Montreal, Canada.
Antenatal risk factors for peanut allergy in children
  • K. Binkley, C. Leaver, J. Ray
  • Medicine
    Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
  • 2011
The risk of childhood peanut allergy was not modified by the following common maternal exposures in pregnancy: Rh immune globulin, folic acid or peanut-containing foods.
Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants.
Is the prevalence of peanut allergy increasing? A 5-year follow-up study in children in Montreal.


Peanut allergy in relation to heredity, maternal diet, and other atopic diseases: results of a questionnaire survey, skin prick testing, and food challenges
Peanut allergy is more common in siblings of people with peanut allergy than in the parents or the general population, and apparently increasing prevalence may reflect a general increase of atopy, which is inherited more commonly from the mother.
Cohort study of peanut and tree nut sensitisation by age of 4 years
It is suggested that 1 in 200 children could have reactions to peanuts and tree nuts by the age of 4 years and a similar number could have asymp- tomatic sensitisation.
The natural history of peanut allergy.
Peanut protein as a major cause of adverse food reactions in patients with atopic dermatitis.
These studies indicate that children with all degrees of atopic dermatitis may benefit from evaluation for food hypersensitivity and show that peanut is a major food protein responsible for these reactions.
Studies of hypersensitivity reactions to foods in infants and children.
Cumulative incidence of atopic disorders in high risk infants fed whey hydrolysate, soy, and conventional cow milk formulas.
It is shown that among infants at high risk of developing atopic disease because of positive family history, exclusive breast feeding or whey hydrolysate formula is associated with a lower incidence and thus a delay in the occurrence of allergic disorders compared with groups fed conventional cow milk or soy formulas.
Transfer of symptomatic peanut allergy to the recipient of a combined liver-and-kidney transplant.
A 22-year-old man with a history of allergic reactions to peanuts was admitted to a hospital in a coma after inadvertently ingesting satay sauce, which contains peanuts, and a case of peanut allergy transmitted through combined liver-and-kidney transplantation is reported.