Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection.

@article{Sather2009FactorsAW,
  title={Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection.},
  author={D Noah Sather and Jakob P Armann and Lance K. Ching and Angeliki Mavrantoni and George E Sellhorn and Zachary R. Caldwell and Xuesong Yu and Blake Philip Wood and Steve Self and Spyros A. Kalams and Leonidas Stamatatos},
  journal={Journal of virology},
  year={2009},
  volume={83 2},
  pages={
          757-69
        }
}
The characterization of the cross-reactive, or heterologous, neutralizing antibody responses developed during human immunodeficiency virus type 1 (HIV-1) infection and the identification of factors associated with their generation are relevant to the development of an HIV vaccine. We report that in healthy HIV-positive, antiretroviral-naïve subjects, the breadth of plasma heterologous neutralizing antibody responses correlates with the time since infection, plasma viremia levels, and the… CONTINUE READING
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