Factors associated with reduced fertility and implantation rates in females mated to acrylamide-treated rats.

@article{Sublet1989FactorsAW,
  title={Factors associated with reduced fertility and implantation rates in females mated to acrylamide-treated rats.},
  author={V H Sublet and Harold Zenick and Michelle K. Smith},
  journal={Toxicology},
  year={1989},
  volume={55 1-2},
  pages={53-67}
}
A series of studies was conducted to examine the role of copulatory dysfunction, spermatotoxicity, and/or impaired fertilization in the reduced rates of fertility and implantation observed in females mated to acrylamide-treated male rats. In initial experiments, males were gavaged with 0, 5, 15, 30, 45, or 60 mg/kg acrylamide (ACR) for 5 days and then mated serially to naive females. ACR treatment reduced fertility and increased pre- and post-implantation loss, primarily over the first 3 weeks… CONTINUE READING

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