Factors associated with prolonged symptoms and severe disease due to Clostridium difficile.

  title={Factors associated with prolonged symptoms and severe disease due to Clostridium difficile.},
  author={Lorraine Kyne and Concepta Merry and BRIAN A. O'CONNELL and A M Kelly and Conor Keane and Desmond O'neill},
  journal={Age and ageing},
  volume={28 2},
OBJECTIVE toxigenic Clostridium difficile is responsible for a spectrum of disease severity ranging from mild diarrhoea to fulminant colitis. This study attempts to determine the proportion of patients in each category of severity and evaluate the risk factors for a more prolonged and complicated course. DESIGN prospective cohort study. SETTING university teaching hospital. SUBJECTS all patients with symptomatic C. difficile infection during 4 months of an outbreak (January-April 1995); n… CONTINUE READING


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