Factors associated with HER2 overexpression in breast cancer: Experience in an Asian developing country.

@article{Tan2009FactorsAW,
  title={Factors associated with HER2 overexpression in breast cancer: Experience in an Asian developing country.},
  author={Gie-Hooi Tan and W Q W Choo and Nur Aishah Mohd Taib and C. P. Yip},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2009},
  volume={10 5},
  pages={837-40}
}
INTRODUCTION The HER2 gene is amplified in up to 30% of human breast cancers, leading to overexpression of the HER2 protein on the cell surface. Overexpression of HER2 is associated with a more aggressive cancer and hence a poorer overall survival. OBJECTIVE To evaluate the association between clinico-pathological features and HER2 overexpression in breast cancer. METHODS This is a retrospective study conducted in the Department of Surgery, University Malaya Medical Centre. The association… CONTINUE READING