Factors affecting the permeability of Pseudomonas aeruginosa cell walls toward lipophilic compounds: effects of ultrasound and cell age.

@article{Rapoport1997FactorsAT,
  title={Factors affecting the permeability of Pseudomonas aeruginosa cell walls toward lipophilic compounds: effects of ultrasound and cell age.},
  author={Natalya Y Rapoport and Alex I Smirnov and Alexander A. Timoshin and Angela M Pratt and William G. Pitt},
  journal={Archives of biochemistry and biophysics},
  year={1997},
  volume={344 1},
  pages={
          114-24
        }
}
The objective of this research was to elucidate the factors effecting the permeability of cell membranes of gram-negative bacteria toward hydrophobic compounds. Ultrasound treatment, cell age, and the phase state of phospholipid membranes were considered. Spin-labeling EPR method was used to quantify the penetration and distribution of a lipophilic spin probe, 16-doxylstearic acid (16-DS), in Pseudomonas aeruginosa cell membranes. This bacterium was chosen because of its reported resistance to… CONTINUE READING

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