Factors affecting the mechanical behavior of collagen hydrogels for skin tissue engineering.

@article{Pensalfini2017FactorsAT,
  title={Factors affecting the mechanical behavior of collagen hydrogels for skin tissue engineering.},
  author={M. Pensalfini and A. E. Ehret and Silvia St{\"u}deli and Daniela Marino and A. Kaech and E. Reichmann and E. Mazza},
  journal={Journal of the mechanical behavior of biomedical materials},
  year={2017},
  volume={69},
  pages={
          85-97
        }
}
The effect of the production factors yielding a functional dermal substitute was investigated by means of monotonic and cyclic uniaxial tensile tests, as well as electron microscopy visualizations. The role of (i) plastic compression, (ii) product incubation, and (iii) cell permanence in the collagenous matrix in order to achieve a skin-like behavior were characterized in terms of material and structural stiffness, in-plane kinematics, and cyclic response, as well as pore size and network… Expand
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