Factors affecting the leukotoxin activity of Fusobacterium necrophorum.

  title={Factors affecting the leukotoxin activity of Fusobacterium necrophorum.},
  author={Zerlinda Y. L. Tan and T G Nagaraja and Muckatira M. Chengappa},
  journal={Veterinary microbiology},
  volume={32 1},
The effect of cultural conditions on the production of leukotoxin by biotypes A and B of F. necrophorum was investigated. Biotypes A and B were grown in prereduced, anaerobically sterilized, brain-heart infusion (BHI) broth. The average leukotoxin titer of culture supernatant was 18 times higher from biotype A strains than from biotype B strains. Leukotoxin activity peaked during the late-log and early-stationary phases of growth, then declined precipitously in both biotypes. F. necrophorum… CONTINUE READING

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