Factors affecting the developmental competence of mouse oocytes grown in vitro: oxygen concentration.

@article{Eppig1995FactorsAT,
  title={Factors affecting the developmental competence of mouse oocytes grown in vitro: oxygen concentration.},
  author={John J. Eppig and Karen Wigglesworth},
  journal={Molecular reproduction and development},
  year={1995},
  volume={42 4},
  pages={447-56}
}
The purpose of this study was to assess the effects of oxygen concentration on the developmental competence of mouse oocytes grown in vitro because oxygen has been shown to affect the nuclear maturation of oocytes (Haidri et al., 1971: J Reprod Fertil 26:409-411) and preimplantation embryo development (Whitten, 1971: Adv Biosci 6:129-139). Oocyte--granulosa cell complexes were isolated from the preantral follicles of 12-day-old mice and cultured for 10 days in serum-free medium equilibrated… CONTINUE READING

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