Factors affecting the detection of enteroviruses in cerebrospinal fluid with coxsackievirus B3 and poliovirus 1 cDNA probes.

@article{Rotbart1985FactorsAT,
  title={Factors affecting the detection of enteroviruses in cerebrospinal fluid with coxsackievirus B3 and poliovirus 1 cDNA probes.},
  author={Harley A. Rotbart and Mariano Jorge Levin and Luis P. Villarreal and Steven M. Tracy and Bert L Semler and Eckard J Wimmer},
  journal={Journal of clinical microbiology},
  year={1985},
  volume={22 2},
  pages={220-4}
}
Enteroviruses are common pathogens of meningitis and encephalitis, and infections are often difficult to distinguish clinically from bacterial and herpetic infections of the central nervous system. An array of enteroviruses added to cerebrospinal fluid in reconstruction experiments were detected by a dot hybridization assay. Optimal handling and processing conditions for infected cerebrospinal fluid were established, and the effect on the hybridization reaction of humoral and cellular… CONTINUE READING