Factors affecting solubilization of the D1 receptor from bovine caudate nucleus.

Abstract

The D1 dopamine receptor was identified using the dopamine agonist 3H-ADTN. The ability of various detergents to solubilize this receptor from bovine caudate nucleus was examined. In order to maintain high affinity binding, receptors were solubilized in the presence of dopamine and manganese. GPP(NH)P reduced the yield of soluble receptors. Of the… (More)

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Cite this paper

@article{Ross1985FactorsAS, title={Factors affecting solubilization of the D1 receptor from bovine caudate nucleus.}, author={Gregory M Ross and Samina B. Bajwa and Ram Kumar Mishra}, journal={Progress in neuro-psychopharmacology & biological psychiatry}, year={1985}, volume={9 5-6}, pages={749-53} }