Factors affecting nuclear export of the 60S ribosomal subunit in vivo.

  title={Factors affecting nuclear export of the 60S ribosomal subunit in vivo.},
  author={T Stage-Zimmermann and Ute Schmidt and Pamela A. Silver},
  journal={Molecular biology of the cell},
  volume={11 11},
In Saccharomyces cerevisiae, the 60S ribosomal subunit assembles in the nucleolus and then is exported to the cytoplasm, where it joins the 40S subunit for translation. Export of the 60S subunit from the nucleus is known to be an energy-dependent and factor-mediated process, but very little is known about the specifics of its transport. To begin to address this problem, an assay was developed to follow the localization of the 60S ribosomal subunit in S. cerevisiae. Ribosomal protein L11b… CONTINUE READING
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