Factors That Control the Tissue-Specific Transcription of the Gene for Phosphoenolpyruvate Carboxykinase-C

@article{Chakravarty2005FactorsTC,
  title={Factors That Control the Tissue-Specific Transcription of the Gene for Phosphoenolpyruvate Carboxykinase-C},
  author={K. Chakravarty and H. Cassuto and L. Reshef and R. Hanson},
  journal={Critical Reviews in Biochemistry and Molecular Biology},
  year={2005},
  volume={40},
  pages={129 - 154}
}
ABSTRACT Transcription of the gene for PEPCK-C occurs in a number of mammalian tissues, with highest expression occurring in the liver, kidney cortex, and white and brown adipose tissue. Several hormones and other factors, including glucagon, epinephrine, insulin, glucocorticoids and metabolic acidosis, control this process in three responsive tissues, liver, adipose tissue, and kidney cortex. Expression of the gene in these three tissues in regulated in a different manner, responding to the… Expand
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