Factors Affecting the Folding of Pseudomonas aeruginosa OprF Porin into the One-Domain Open Conformer

Abstract

Pseudomonas aeruginosa OprF is a largely monomeric outer membrane protein that allows the slow, nonspecific transmembrane diffusion of solutes. This protein folds into two different conformers, with the majority conformer folding into a two-domain conformation that has no porin activity and the minority conformer into a one-domain conformation with high… (More)
DOI: 10.1128/mBio.00228-10

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