Factors (TAFs) required for activated transcription interact with TATA box-binding protein conserved core domain.

@article{Zhou1993FactorsR,
  title={Factors (TAFs) required for activated transcription interact with TATA box-binding protein conserved core domain.},
  author={Q. F. Zhou and Thomas G. Boyer and A. Berk},
  journal={Genes & development},
  year={1993},
  volume={7 2},
  pages={180-7}
}
TFIID is a multisubunit protein containing the TATA box-binding polypeptide (TBP) and associated factors (TFIID-TAFs) required for activated transcription by RNA polymerase II. TBPs from different eukaryotes contain a highly conserved carboxy-terminal domain and very divergent amino-terminal domains. Earlier studies proposed that the amino-terminal domains of metazoan TBPs are required for activated transcription. However, we report that a human TFIID complex containing an amino-terminal… CONTINUE READING