Factorial designed 5-fluorouracil-loaded microsponges and calcium pectinate beads plugged in hydroxypropyl methylcellulose capsules for colorectal cancer

Abstract

INTRODUCTION The work was aimed to develop an enteric-coated hydroxypropyl methylcellulose (HPMC) capsules (ECHC) plugged with 5-fluorouracil (5-FU)-loaded microsponges in combination with calcium pectinate beads. MATERIALS AND METHODS The modified quasi-emulsion solvent diffusion method was used to prepare microsponges. A 3(2) factorial design was… (More)
DOI: 10.4103/2230-973X.167688

Topics

Cite this paper

@inproceedings{Gupta2015FactorialD5, title={Factorial designed 5-fluorouracil-loaded microsponges and calcium pectinate beads plugged in hydroxypropyl methylcellulose capsules for colorectal cancer}, author={Ankita Gupta and Gaurav Tiwari and Ruchi Tiwari and Rishabh Srivastava}, booktitle={International journal of pharmaceutical investigation}, year={2015} }