Factor analysis of the metabolic syndrome: obesity vs insulin resistance as the central abnormality

@article{Anderson2001FactorAO,
  title={Factor analysis of the metabolic syndrome: obesity vs insulin resistance as the central abnormality},
  author={P. Anderson and JAJH Critchley and J Chan and C W Cockram and ZSK Lee and G. raham Neil Thomas and Brian Tomlinson},
  journal={International Journal of Obesity},
  year={2001},
  volume={25},
  pages={1782-1788}
}
OBJECTIVES: To evaluate whether there is one central abnormality contributing to the conditions associated with the metabolic syndrome (MES), or whether one abnormality is contributing on multiple levels.METHODS: We recruited 145 Chinese subjects aged 17–68 y with varying degrees of insulin-sensitivity (IS): 33 healthy, 59 with type 2 diabetes mellitus, 32 essential hypertensives and 21 dyslipidaemics. IS was evaluated by the short insulin sensitivity test using a 0.1 U/kg intravenous bolus… CONTINUE READING