Factor analysis of attentional set-shifting performance in young and aged mice

@inproceedings{Tanaka2010FactorAO,
  title={Factor analysis of attentional set-shifting performance in young and aged mice},
  author={Shoji Tanaka and Jared W. Young and Jodi E. Gresack and Mark A. Geyer and Victoria B Risbrough},
  booktitle={Behavioral and Brain Functions},
  year={2010}
}
Executive dysfunction may play a major role in cognitive decline with aging because frontal lobe structures are particularly vulnerable to advancing age. Lesion studies in rats and mice have suggested that intradimensional shifts (IDSs), extradimensional shifts (EDSs), and reversal learning are mediated by the anterior cingulate cortex, the medial prefrontal cortex, and the orbitofrontal cortex, respectively. We hypothesized that the latent structure of cognitive performance would reflect… CONTINUE READING
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