Factor XIII activity mediates red blood cell retention in venous thrombi.

@article{Alemn2014FactorXA,
  title={Factor XIII activity mediates red blood cell retention in venous thrombi.},
  author={Maria Mercedes Alem{\'a}n and James R Byrnes and Jian-guo Wang and Reginald Tran and Wilbur A Lam and Jorge A. Di Paola and Nigel Mackman and Jay L. Degen and Matthew J. Flick and Alisa S. Wolberg},
  journal={The Journal of clinical investigation},
  year={2014},
  volume={124 8},
  pages={3590-600}
}
Venous thrombi, fibrin- and rbc-rich clots triggered by inflammation and blood stasis, underlie devastating, and sometimes fatal, occlusive events. During intravascular fibrin deposition, rbc are thought to become passively trapped in thrombi and therefore have not been considered a modifiable thrombus component. In the present study, we determined that… CONTINUE READING